The Friuli population cohorts
The Friuli population cohorts were collected as part of the WHO MONICA surveys. The Friuli area covers three provinces of north-east Italy (Friuli-Venezia-Giulia) recruited using a single stage sampling frame from the official Regional Health Roll stratified by Health Unit (combination of municipalities covering 40,000 inhabitants), sex and 5-year age group. Four cohorts were recruited, the BiomarCaRE project will focus on Cohort 3 collected in 1994 (participation rate, 71%) consisting of men and women aged 25-64 years and cohort 4 collected in 1995-96, (participation rate, 90% consisting of men and women aged 45-64 years. Follow up through registry linkage is available until 1998 collected through the framework of the Progetto Cuore.